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  <xs:element id="iclr_InterestRateCapAndInterestRateSwapMember" abstract="true" name="InterestRateCapAndInterestRateSwapMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="iclr_RestOfWorldMember" abstract="true" name="RestOfWorldMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="iclr_RestrictedStockUnitsTwentyThirteenMember" abstract="true" name="RestrictedStockUnitsTwentyThirteenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="iclr_ChangeInAdvancePaymentsNettedAgainstUnbilledContractsReceivable" abstract="false" name="ChangeInAdvancePaymentsNettedAgainstUnbilledContractsReceivable" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iclr_LongTermDebtCurrentMaturitiesGross" abstract="false" name="LongTermDebtCurrentMaturitiesGross" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="iclr_FacilityLiabilityMember" abstract="true" name="FacilityLiabilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="iclr_IncreaseDecreaseInContractWithCustomerAssetGrossCurrent" abstract="false" name="IncreaseDecreaseInContractWithCustomerAssetGrossCurrent" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
</xs:schema>
