FORM 6-K


SECURITIES AND EXCHANGE COMMISSION


Washington, D.C. 20549


Report of Foreign Private Issuer
Pursuant to Rule 13a-16 under
the Securities Exchange Act of 1934


For the month ended February, 2011


ICON plc
(Registrant's name)


0-29714
(Commission file number)


South County Business Park, Leopardstown, Dublin 18, Ireland
(Address of principal executive offices)

Ciaran Murray, CFO
South County Business Park Leopardstown, Dublin 18, Ireland.
Ciaran.Murray@iconplc.com
0011-353-1-291-2000
(Name, telephone number, email and/or facsmile number and address of Company contact person)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

              Yes___X___                                   No_______

Indicate by check mark whether the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):

              Yes______                                    No___X___

Indicate by check mark whether the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):

              Yes______                                    No___X___

Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

              Yes_______                                   No___X___

If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b):82      N/A

EXHIBIT LIST

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Exhibit 99.1

ICON Reports Full-Year 2010 Revenue of $900m and EPS of $1.44

Highlights – Full Year 2010 and Fourth Quarter ended December 31.

* 2010 net revenue increased 1.4% to $900 million, or 3.1% on a constant currency basis. Q4 net revenues increased 2.1% or 5.6% on a constant currency basis to $232 million.

* 2010 operating income was 10.2% or $92 million. Q4 operating income was 9.5% or $22 million.

* Diluted 2010 EPS was $1.44. EPS for Q4 was 36 cents.

* 2010 net new business awards were $1.05 billion, a book-to-bill of 1.16x. Q4 net business awards were $237 million, a book-to-bill of 1.0x.

* Guidance for 2011 is for revenue in the range of $945 - $980 million, growth of 5 – 9%, and EPS in the range of $1.10 to $1.25

DUBLIN--(BUSINESS WIRE)--February 24, 2011--ICON (NASDAQ:ICLR) (ISIN:IE0005711209), a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, today reported its financial results for the full year and fourth quarter ended December 31, 2010.

Net revenues for 2010 grew 1.4% to $900 million, representing a constant currency increase of 3.1% year on year.

Operating income was $92 million, representing 10.2% of revenue, compared to $116.3 million and 13.1% last year. This comprised clinical services operating income of $104.8 million or 12.5% and central lab operating losses of $12.8 million.

Net income was $87.1 million, a net margin of 9.7%, compared to $91.6 million last year and 10.3% of revenue. Diluted EPS for 2010 was $1.44 per share compared with $1.53 in 2009.

For the fourth quarter, net revenues grew 2% to $232.1 million. On a constant currency basis the increase was 5.6%.

Operating income was $22 million, representing 9.5% of revenue, compared to $29.6 million or 13% for the same quarter last year. This comprised clinical services operating income of $26 million or 12.1% and a central lab operating loss of $4 million.

Net income was $22 million, compared with $23.9 million last year, producing a diluted earnings per share of 36c compared to 40c in the same quarter last year.

Days sales outstanding, comprising accounts receivable and unbilled revenue less payments on account, were 37 days at December 31, 2010. This compares to 33 days at December 31, 2009.

For the quarter ended December 31, 2010, cash provided by operating activities was $31.9 million and capital expenditure was $7.1 million. Full year 2010 cash flow from operating activities was $87.4 million and capital expenditure was $31 million. As a result, the company’s net cash amounted to $256 million at December 31, 2010 compared to $194 million of net cash at December 31, 2009.

Commenting on the results, CEO Peter Gray said “2010 has been a challenging year, as some parts of our business, and particularly our central lab, absorbed the impact of the weak business environment in 2009. 2010 has also seen an acceleration in the pace of change in the biopharmaceutical industry, which is creating strong opportunities for the future, but is requiring us to adapt our business model and structures to effectively capitalise on these. This process continues, and we are making significant investments to build additional capabilities, to leverage our scale more effectively, and to implement process and systems change necessary to prosper in the evolving market. We do not expect the benefit of our investments to be realised until late 2011 and into 2012. Consequently we are guiding revenue for 2011 in the range of $945 – $980 million, representing growth of 5-9%, and EPS in the range of $1.10 - $1.25.”

In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), this press release contains certain non-GAAP financial measures, including non-GAAP operating and net income and non-GAAP diluted earnings per share. While non-GAAP financial measures are not superior to or a substitute for the comparable GAAP measures, ICON believes certain non-GAAP information is useful to investors for historical comparison purposes.

The company will hold its fourth quarter conference call today, February 24, 2011 at 9:00 EST [14:00 Ireland & UK]. This call and linked slide presentation can be accessed live from our website at http://www.iconplc.com. A recording will also be available on the website for 90 days following the call. In addition, a calendar of company events, including upcoming conference presentations, is available on our website under “Investors”. This calendar will be updated regularly.

The statements made in this press release may contain forward-looking statements that involve a number of risks and uncertainties. In addition to the matters described in this Press Release, the ability to maintain large client contracts or enter into new contracts, maintain client relationships and the ability to manage the opening of new offices, the integration of new business mergers and acquisitions, as well as other risks and uncertainties detailed from time to time in SEC reports filed by ICON, including its Form 20-F, F-1, S-8 and F-3, may affect the actual results achieved by ICON. ICON disclaims any intent or obligation to update these forward-looking statements.

ICON plc is a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries. The Company specialises in the strategic development, management and analysis of programs that support clinical development - from compound selection to Phase I-IV clinical studies. With headquarters in Dublin, Ireland, ICON currently, operates from 77 locations in 39 countries and has approximately 7,700 employees. Further information is available at www.iconplc.com.

ICON/ICLR-F

CONTACT:
ICON plc
Contact : Investor Relations 1-888-381-7923
or
Ciaran Murray Chief Financial Officer + 353 –1-291-2000
or
Brendan Brennan SVP Corp Fin + 353 –1-291-2000
or
Sam Farthing VP Investor Relations + 353 –1-291-2000