DUBLIN--(BUSINESS WIRE)--
      ICON plc, (NASDAQ:ICLR) (ISIN:IE0005711209), a global provider of
      outsourced development services to the pharmaceutical, biotechnology and
      medical device industries, and Proteome Sciences (AIM:PRM) a leading
      provider of protein biomarker discovery, validation, and assay
      development services, today announced the formation of a strategic
      alliance to provide pharmaceutical companies with an expanded biomarker
      solution to allow earlier assessments in the development of new
      medicines.
    
    
      Through the alliance with Proteome's PS Biomarker Services™, ICON is
      strengthening its current biomarker solution to include an integrated
      suite of labeling, separation and mass spectrometry technologies for
      protein and peptide profiling in complex biological materials.
    
    
      ICON and Proteome Sciences are already engaged in their first joint
      project which is the development of a mass spectrometry assay for a key
      biomarker for an international pharmaceutical development company.
    
    
      Commenting on the initiation of this project, John Allinson, VP
      Biomarker Lab Services, ICON Development Solutions stated: "We are
      extremely pleased to be entering this long-term partnership with
      Proteome Sciences which allows us to offer our clients access to state
      of the art protein and peptide profiling and rapid development of mass
      spectrometry assays through PS Biomarker Services™. This complements
      ICON's extensive portfolio of biomarker development and analysis
      services to help sponsors identify, implement and interpret the right
      biomarkers to inform their pre-clinical and clinical drug development."
    
    
      Dr. Ian Pike, Proteome's Chief Operating Officer added: "We are
      delighted to be partnering with the team at ICON Development Solutions
      to provide their clients with a complete biomarker solution, including
      PS Biomarker Discovery Services™ as part of wider clinical development
      programs. The unique power of our proprietary technology platforms to
      identify and validate key protein biomarkers of disease and response to
      treatment is clearly being recognized and used by the pharmaceutical
      industry.
    
    
      Notes to Editors:
    
    
      About ICON plc
    
    
      ICON plc is a global provider of outsourced development services to the
      pharmaceutical, biotechnology and medical device industries. The Company
      specialises in the strategic development, management and analysis of
      programmes that support clinical development - from compound selection
      to Phase I-IV clinical studies. ICON currently has around 7,700
      employees, operating from 71 offices in 39 countries. For more
      information visit www.iconplc.com.
    
    
      About Proteome Sciences
    
    
      Proteome Sciences is a global leader in applied proteomics and uses high
      sensitivity proprietary technologies for protein biomarker discovery,
      validation and assay development. The Company's own research has
      discovered a large number of novel protein biomarkers in key human
      diseases and is focused mainly in neurological/neurodegenerative
      conditions and in cancer. It has discovered and patented blood
      biomarkers, including Alzheimer's disease, stroke, brain damage and lung
      cancer for diagnostic and treatment applications. These biomarkers are
      available for outlicensing. The first blood test for lung cancer using
      Proteome Sciences' biomarkers was launched in the USA in 2009 and
      received Medicare reimbursement in 2010. Its PS Biomarker Services
      provides ISO 9001: 2008 accredited facilities in Frankfurt, Germany,
      using proprietary isobaric and isotopic Tandem Mass Tags® (TMT®)
      to discover protein biomarkers, and reference materials combined with
      isotope dilution mass spectrometry. Highly multiplexed assays can be
      developed rapidly and are suitable for screening hundreds of candidate
      biomarkers in validation studies. Assays for validated biomarkers can be
      transferred for immunoassay development. Proteome Sciences, based in
      Cobham, UK, has facilities in London and Frankfurt and delivers
      outsourced proteomics services and proprietary biomarkers to
      pharmaceutical, biotechnology and diagnostics companies. Visit http://www.proteomics.com.
    
    
      ICON/ICLR-G
    
 
    
      ICON plc
Emily Brand
Corporate Communications Manager
+353-1-2912665
Emily.brand@iconplc.com
or
Proteome
      Sciences plc
Dr. Ian Pike, Chief Operating Officer
Tel:
      +44 (0)1932 865065
ian.pike@proteomics.com
or
Nominated
      Adviser - Singer Capital Markets Limited
Shaun Dobson / Claes
      Spång
Tel: +44 (0)20 3205 7500
or
IKON Associates
Adrian
      Shaw
Tel: +44 (0)1483 271291
Mobile: +44 (0)7979 900733
Email:
      adrian@ikonassociates.com
or
Redleaf
      Communications Limited
Anna Dunkin / Lucy Salaman
Tel: +44
      (0)20 7566 6700
Email: proteome@redleafpr.com
    
Source: ICON plc
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